Gilbert’s syndrome

Injury	Disease	Nutrition	Poison

Symptoms	Surgery	Test	Special Topic

Digestive system

Digestive system organs

Gilbert’s syndrome

Definition:

Gilbert's disease is a multifactorial inherited disorder that affects the way bilirubin is processed by the liver and causes jaundice.

Alternative Names:

Icterus intermittens juvenilis; Low-grade chronic hyperbilirubinemia; Familial non-hemolytic-non-obstructive jaundice; Constitutional liver dysfunction; Unconjugated benign bilirubinemia

Causes, incidence, and risk factors:

Gilbert's disease is common, affecting up to 10% of some Caucasian populations. The most significant symptom of this condition is jaundice. Affected individuals ordinarily have no jaundice. However, jaundice appears under conditions of exertion, stress, fasting, and infections. The condition is usually benign.

Review Date: 8/2/2005
Reviewed By: Courtney W. Houchen, M.D., Division of Gastroenterology, Washington University School of Medicine, St. Louis, MO. Review provided by VeriMed Healthcare Network.

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