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Ectopic ADH secretion

Definition:

ADH is anti-diuretic hormone produced naturally by the hypothalmus and released by the pituitary gland. An anti-diuretic reduces the amount of water your body eliminates.

Ectopic ADH secretion is the release of ADH from an abnormal location within the body. (Ectopic means "unnatural.") The abnormal release of the hormone cecreases the body's ability to eliminate water, causing fluid to build-up in the body. Hyponatremia (low sodium in your blood) can result.



Causes, incidence, and risk factors:

The most common cause of ectopic ADH secretion is cancer. See also syndrome of inappropriate ADH secretion (SIADH) and the ADH test.



References:

Lin M, Liu SJ, Lim, IT. Disorders of Water Imbalance. Emerg Med Clin North Am - 2005 Aug; 23(3); 749-770.




Review Date: 8/1/2005
Reviewed By: A.D.A.M. editorial and Nikheel S. Kolatkar, MD, Clinical and Research Fellow, Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Harvard Medical School, Boston, MA. Review provided by VeriMed Healthcare Network.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2004 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

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