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There is no specific treatment for renal papillary necrosis. If analgesic nephropathy is suspected as the cause, stop the use of suspected medications. This may allow healing over time.
If nephropathy is a result of diabetes or sickle cell anemia, control of these disorders is important to reduce renal papillary necrosis. Renal failure should be treated as appropriate. The treatment of chronic or recurrent urinary tract infections may include antibiotics.
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