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Central nervous system
Central nervous system


Neurosyphilis

Symptoms:
  • Headache
  • Stiff neck
  • Irritability
  • Poor concentration
  • Mental confusion
  • Depression
  • Visual disturbances
  • Abnormal reflexes
  • Abnormal gait (walk)
  • Incontinence
  • Dementia
  • Weakness, numbness of lower extremities
  • Muscle function/feeling loss
  • Muscle contractions
  • Muscle atrophy
Note: There may be no symptoms (in the asymptomatic form)

Signs and tests:

Tests to detect syphilis include detection of antibodies in blood. These are non-treponemal tests (VDRL, RPR). These are not specific and are used as screening tests. If positive the diagnosis of syphilis is confirmed using treponemal tests (e.g., FTA-Abs or MHATP). In neurosyphilis, it is important to test for VDRL in the spinal fluid.

Tests to evaluate the nervous system may include:


Review Date: 2/7/2005
Reviewed By: Luc Jasmin, MD, PhD, Departments of Anatomy & Neurological Surgery, University of California, San Francisco, CA. Review provided by VeriMed Healthcare Network.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2004 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

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