Dementia

Injury	Disease	Nutrition	Poison

Symptoms	Surgery	Test	Special Topic

Central nervous system

Overview

Symptoms

Treatment

Prevention

Dementia

Definition:

Dementia is a loss of brain function. It is not a single disease. Instead, dementia refers to a group of illnesses that involve memory, behavoir, learning, and communicating problems. The problems are progressive, which means they slowly get worse.

Alternative Names:

Chronic brain syndrome; Lewy body dementia; DLB; Vascular dementia

Causes, incidence, and risk factors:

The two major causes of degenerative (non-reversible) dementia are Alzheimer's disease and vascular dementia (loss of brain function due to a series of small strokes). The two conditions often occur together.

Dementia with Lewy bodies (DLB) is a leading cause of degenerative dementia in elderly adults. This condition is linked to abnormal protein structures in certain areas of the brain. The structures and symptoms of DLB are associated with Alzheimer's disease, but it is uncertain whether DLB is a sub-type of Alzheimer's or separate disease. There is no cure for DLB or Alzheimer's.

Conditions that damage blood vessels or nerve structures of the brain can also lead to dementia.

Treatable causes of dementia include normal pressure hydrocephalus, brain tumors, and dementia due to metabolic causes, thyroid conditions, low vitamin B12 levels, and infections.

Dementia may be diagnosed when a patient has two or more problems in brain function. Problems may involve language, memory, perception, emotional behavior or personality, and cognitive skills (such as calculation, abstract thinking, or judgment). Dementia usually first appears as forgetfulness. Other symptoms may only be seen during a medical exam or with cognitive tests.

Dementia usually occurs in older age. Dementia is rare in people under age 60. The risk for dementia increases as a person gets older.

References:

Alva G. Alzheimer disease and other dementias. Clin Geriatr Med. 2003; 19(4): 763-76.

American Academy of Neurology. About Dementia. Neurology. 2004; 63(10); E20.

Moore DP, Jefferson JW. Handbook of Medical Psychiatry. 2nd ed. St. Louis, Mo: Mosby; 2004:283-286.

Goetz, CG. Textbook of Clinical Neurology. 2nd ed. St. Louis, Mo: WB Saunders; 2003: 705-708.

Review Date: 5/10/2006
Reviewed By: Daniel Kantor, M.D., Director of the Comprehensive MS Center, Neuroscience Institute, University of Florida Health Science Center, Jacksonville, FL. Review provided by VeriMed Healthcare Network.

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