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Treatment includes general measures to control gastroesophageal reflux, medications, photodynamic therapy (PDT), and surgery. Treatment may be important even if the patient doesn't feel any symptoms.
General measures include:
- Weight reduction
- Avoiding lying down after meals
- Sleeping with the head of the bed elevated
- Taking medication with plenty of water
- Avoiding dietary fat, chocolate, caffeine, and peppermint because they may cause lower esophageal pressure
- Avoiding alcohol and tobacco
Medications to relieve symptoms and control gastroesophageal reflux include antacids after meals and at bedtime, histamine H2 receptor blockers, proton pump inhibitors, cholinergic agents, and promotility agents.
Surgery to remove a portion of the esophagus (resection of the esophagus) may be indicated, if a biopsy shows the type of cellular changes that tend to lead to cancer (dysplasia).
Photodynamic therapy (PDT) is a newly approved option that may allow you to avoid surgery. PDT involves the use of a special laser delivery device, called an esophageal balloon, along with a drug called Photofrin. Together, the laser balloon and medication lead to ablation of the abnormal cells lining the esophagus without affecting the normal tissue.
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