Methylmalonic acidemia

Injury	Disease	Nutrition	Poison

Symptoms	Surgery	Test	Special Topic

Overview

Symptoms

Treatment

Prevention

Methylmalonic acidemia

Treatment:

Treatment consists of dietary supplementation with cobalamin, carnitine, and protein restriction.

If cobalamine supplementation doesn't help, a diet restricting isoleucine, threonine, methionine, and valine may be useful.

Expectations (prognosis):

Unfortunately, affected patients may not survive their first attack.

Complications:

Coma
Death

Calling your health care provider:

Parents or care-givers of a child with a first seizure should immediately seek medical attention. Infants with failure-to-thrive or developmental delays should see a pediatrician. Adults and children with strokes or acute mental status changes should seek immediate medical attention.

Review Date: 8/1/2005
Reviewed By: Nikheel S. Kolatkar, MD, Clinical and Research Fellow, Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Harvard Medical School, Boston, MA. Review provided by VeriMed Healthcare Network.

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