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Selenium deficiency may occur in patients fed intravenously for long periods of time.
Keshan disease is caused by a deficiency of selenium. This leads to an abnormality of the heart muscle. Keshan disease claimed the lives of many children in China until the relationship to selenium was discovered and selenium supplements were provided.
Cattle grazing in selenium-rich soil have shown toxicity caused by increased levels of selenium. The cattle developed muscle, visual, and heart problems.
The amount of selenium that would cause toxicity in humans is not known. Excess selenium intake can cause problems with the strength of teeth and the tooth enamel. Other problems may include loss of teeth, hair, and nails. Skin inflammation, nausea, and fatigue can also occur.
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