Hydromorphone overdose

Injury	Disease	Nutrition	Poison

Symptoms	Surgery	Test	Special Topic

Overview

Symptoms

Treatment

Hydromorphone overdose

Alternative Names:

Dilaudid overdose; Palladone overdose

Symptoms:

Nervous system

Drowsiness
Dizziness
Lightheadedness
Confusion
Coma
Muscle twitches
Weakness
Loss of consciousness

Lungs

Heart and blood

Weak pulse
Low blood pressure
Fatigue

Gastrointestinal

Spasms of the stomach and intestines

Skin

Bluish colored fingernails and lips
Cold, clammy skin

Eyes, ears, nose, and throat

Pinpoint pupils

Warning: A severe overdose of hydromorphone can cause death.

References:

Drummer OH. Recent trends in narcotic deaths. Ther Drug Monit. 2005 Dec;27(6):738-40.

Everett S. Narcotic toxity. eMedicine. January 7, 2005. Available at: http://www.emedicine.com/emerg/topic330.htm (accessed March 18, 2006).

US Food and Drug Administration. FDA Asks Purdue Pharma to Withdraw Palladone for Safety Reasons. Rockville, MD: National Press Office; July 13, 2005. Release P05-42.

Review Date: 3/19/2006
Reviewed By: Janeen R. Azare, PhD, MSPH, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY. Review provided by VeriMed Healthcare Network.

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