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Nikolsky's sign
Nikolsky's sign
Skin layers
Skin layers


Nikolsky’s sign

Home Care:

There is no home care for the majority of conditions associated with a positive Nikolsky's sign -- most affected people are hospitalized. Pemphigus is a chronic disease and is treated both at home and in the hospital.



Call your health care provider if:
  • you or your child develop loosening, redness, and blistering of the skin without an obvious cause.

Note: This finding is usually discovered by the health care provider.



What to expect at your health care provider's office:

The affected person will be hospitalized, as the conditions associated with Nikolsky's sign are serious. Medical history is obtained and a physical examination performed. Intravenous fluid and intravenous antibiotics may be used.

Medical history questions documenting Nikolsky's sign in detail may include:

  • When did you first notice that the skin was red or blistered?
  • What other symptoms occur at the same time?



Review Date: 5/3/2006
Reviewed By: Michael S. Lehrer, M.D., Department of Dermatology, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2004 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

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