The palpebra are the upper and lower eyelids which, viewed together, make up the shape of the eye. A line drawn from inner corner to outer corner determines the slant of the eye, or palpebral slant. Slanting and retention of the epicanthal fold are normal in persons of Asian descent. Abnormal slanting of the eye may be associated with some genetic disorders and syndromes. The most commonly recognized syndrome associated with an abnormal palpebral slant is Down syndrome. A fold of skin (epicanthal fold) is often also present in the inner corner of the eye in Down syndrome.
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