B and T cell screen

Injury	Disease	Nutrition	Poison

Symptoms	Surgery	Test	Special Topic

Overview

Risks

Results

B and T cell screen

Alternative Names:

Direct immunofluorescence; E-rosetting; T and B lymphocyte assays; B and T lymphocyte assays

Normal Values:

Values vary from laboratory to laboratory, and depend on testing technique, but typically, T cells comprise 68% to 75% of total lymphocytes and B cells 10% to 20%.

What abnormal results mean:

Abnormal T and B cell counts suggest possible diseases. Further testing is indicated to confirm any of the suggested diagnosis.

An increased T cell count may suggest:

An increased B cell count may suggest:

A decreased T cell count may suggest:

congenital T-cell deficiency disease
- Nezelof syndrome
- DiGeorge syndrome
- Wiskott-Aldrich syndrome
B cell proliferative disorders
- acquired immunodeficiency syndrome
- chronic lymphocytic leukemia
- Waldenstrom's macroglobulinemia

A decreased B cell count may suggest:

acute lymphoblastic leukemia
congenital immunoglobulin deficiency disorders
acquired immunoglobulin deficiency disorders

Review Date: 10/27/2005
Reviewed By: Frank A. Greco, M.D., Ph.D., Director, Biophysical Laboratory, The LaheyClinic, Burlington, MA. Review provided by VeriMed Healthcare Network.

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