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Infant blood sample
Infant blood sample


Neonatal cystic fibrosis screening

Alternative Names:
Cystic fibrosis screening - neonatal; Immunoreactive trypsinogen; IRT test 

What the risks are:

Risks associated with the test include:

  • Infection (a slight risk any time the skin is broken)
  • Parental anxiety over false positive tests
  • False reassurance over false negative tests


Special considerations:

The IRT level does not indicate the severity of the CF. False-positives may occur.



References:
Gross, SD, Boyle, CA, Botkin, JR, et al. Newborn Screening for Cystic Fibrosis:Evaluation of Benefits and Risks and Recommendations for State Newborn Screening Programs. MMWR. 2004;53(RR13);1-36.


Review Date: 5/16/2005
Reviewed By: A.D.A.M. Editorial. Previously reviewed by John Goldenring, M.D., MPH, Department of Pediatrics, Children's Hospital, San Diego, CA. Review provided by VeriMed Healthcare Network.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2004 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

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