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Because LDH can be found in many tissues in the body, total LDH is not specific for heart disease. Normally, the concentration of LDH-2 is greater than LDH-1. However, after a heart attack, the concentration of LDH-1 is generally higher than that of LDH-2. This is called a "flipped" LDH pattern. The LDH level rises within 24 - 72 hours after a heart attack, peaks in 3 - 4 days, and returns to normal in about 14 days.
Greater-than-normal LDH isoenzyme levels may be seen in:
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