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Skin tests and food allergy tests carry a risk that you will experience an allergic reaction when exposed to the allergens. Some sensitive persons will (rarely) experience a life-threatening anaphylactic reaction.
Penicillin and closely related medications are the only drugs that can be tested using skin tests. Skin tests for other drugs are at best non-informative and can be dangerous.
Tests that are not proven as valid include cytotoxic testing, in which foods are mixed in a test tube with a sample of the person's blood and then the white blood cells are observed for a change in shape. Another unproven testing method is "provocation and neutralization" testing, in which the person is injected with a food or other substance and, if there is an allergic reaction, are injected with more of the substance to "neutralize" the response. This can be very dangerous!.
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