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A normal result shows no antibodies to Brucella. However, during the first few days to weeks of exposure to an antigen, there may be very little antibody production. As brucellosis progresses, more antibodies will be present. If brucellosis is suspected, the test may need to be repeated 10 days to 2 weeks after the first test, to watch for this rise.
Infection with other bacteria, such as Yersinia, Francisella, and Vibrio, and immunizations can make the test falsely positive.
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