HLA-B27 antigen

Injury	Disease	Nutrition	Poison

Symptoms	Surgery	Test	Special Topic

Blood test

Overview

Risks

Results

HLA-B27 antigen

Alternative Names:

Human leukocyte antigen B27

Normal Values:

HLA-B27 is found in 5 - 7% of Caucasian people without autoimmune disease.

What abnormal results mean:

A positive test indicates a greater-than-average risk for developing:

Ankylosing spondylitis
Reiter's syndrome
Sacroiliitis (inflammation of the sacroiliac joint)

In the presence of suggestive clinical findings, a positive HLA-B27 test may confirm the diagnosis.

Review Date: 4/29/2005
Reviewed By: Frank A. Greco, M.D., Ph.D., Director, Biophysical Laborartory, The Lahey Clinic, Burlington, MA. Review provided by VeriMed Healthcare Network.

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