Acetylcholine receptor antibody

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Blood test

Overview

Risks

Results

Acetylcholine receptor antibody

Definition:

Acetylcholine receptor antibody is an antibody found in the blood of people with myasthenia gravis.

The acetylcholine receptor antibody attacks receptors for the neurotransmitter acetylcholine, which sends signals from nerves to muscles and from nerve to nerve in the brain. The antibody prevents transmission of the signal and causes muscle weakness.

How the test is performed:

A blood test can detect the presence of these antibodies.

How to prepare for the test:

No special preparation is required.

How the test will feel:

There may be a slight stinging or pricking sensation when blood is drawn, but this is usually mild and brief.

Why the test is performed:

This is a diagnostic test for myasthenia gravis. About 85% of people with generalized myasthenia and 60% of people with ocular myasthenia will have acetylcholine receptor antibodies in their blood.

Review Date: 4/28/2005
Reviewed By: Chitra R. Uppaluri, M.D., Clinical Assistant Professor of Medicine, Saint Louis University, St. Louis, MO. Review provided by VeriMed Healthcare Network.

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