Gastric tissue biopsy is obtained via a procedure known as an upper endoscopy. You may be given a sedative (medicine to make you drowsy), or narcotic (powerful pain-killing medicine), to relieve anxiety and discomfort before this test. A local anesthetic (numbing medicine) is sprayed into the mouth and throat area. A flexible tube is passed through the mouth, down the esophagus (the food pipe), and enters the stomach. The tube may pass through to the duodenum if necessary. The tube allows the health care provider to see the various parts of the upper intestinal tract and take tissue samples of certain areas. The samples are then sent for laboratory and pathology examination.
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