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In myasthenia gravis, the muscles will improve immediately following the Tensilon. The maximum benefit only lasts several minutes.
In myasthenic crisis (worsening of the disease that requires anticholinesterase therapy), there is a brief improvement in the muscle strength.
In cholinergic crisis (overdose of anticholinesterase), Tensilon will exaggerate the muscle weakness.
Additional conditions under which the test may be performed include Lambert-Eaton syndrome.
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