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Heart transplant process
You
can call (352) 265-0751 to make a referral to the heart
transplant program at the Shands Transplant Center at the
University of Florida.
In
order to prepare you mentally for the heart transplant,
it is important to understand what you can expect. Being
informed and prepared for the transplant can improve your
recovery.
Notification | Preparation
| Surgery | CICU
| Equipment | Stay
| Care | Exercise
| Immune system and medication
Notification of transplant
When a new heart becomes available, the heart transplant
coordinator contacts you via telephone. If the coordinator
can't reach you, he or she will use the beeper or pager
system. If you are paged at any time, call Shands at UF
at (352) 265-0111 and ask the operator to page the heart
transplant coordinator on call.
Inform
the coordinator if you have had any of the following in
the past week:
-
Fever
-
Nausea
- Vomiting
- Diarrhea
- Cough
-
Sputum
-
Drainage
-
Antibiotics
Once
contacted, you should come to the hospital with as little
delay as possible. The coordinator will have estimated your
travel time so please use caution while driving to Shands
at UF. You may also contact Angel Flight of Florida to arrange
transportation.
Do not
eat or drink anything after you have been contacted about
the transplant. When you arrive at the hospital, the coordinator
will instruct you where to go for check-in preparation for
surgery.
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Preparation
for surgery
Prior to surgery, you will be examined by the coordinator,
the surgeons and anesthesiologists. The examinations include:
-
Chest X-ray
-
Blood samples
-
Placement of an IV catheter in your arm or hand - IV Cyclosporin
-
Dose of Imuran or Cellcept by mouth
-
Vital signs check of blood pressure, pulse and temperature
Before
surgery, you will be asked to sign a consent form giving
the surgeons and anesthesiologists permission to perform
the heart transplant and blood transfusions.
During
most of the preparation period, your family will be allowed
to stay and visit with you.
Once
you go to the Operating Room your family is directed to
the waiting room. The coordinator will stay in touch with
your family throughout the time of surgery and keep them
informed of your progress.
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Heart
transplant surgery
The time your surgery begins will depend on the progress
of our team of surgeons and specialists who have gone to
retrieve your new heart. After your new heart arrives, the
donor team must determine that the heart is right for you.
After the heart is tested and approved, the surgery begins.
Once
you are in the Operating Room, doctors and nurses will further
prepare you for surgery. The anesthesiologist will give
you medications to help you relax and sleep.
There
are two specific surgical approaches to the heart transplantation.
The surgeon will decide which is best for you depending
upon your anatomy, past surgical history and how much time
is available before your new heart arrives. You will be
supported on a heart-lung (cardiopulmonary bypass) machine
while your old heart is being removed and your new heart
is being transplanted.
When
your surgery begins, the doctors prepare you to receive
your new heart. The surgery will take six to seven hours
from the time you go into the OR and the time you come out.
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Cardiovascular
Intensive Care Unit
After surgery, you begin recovering in the Cardiovascular
Intensive Care Unit (CICU). As soon as you are settled in
your room, your family will be allowed to visit. You are
at a high risk for infection so we must limit your of visitors
and visiting hours. Only immediate family members are allowed
to visit you in the CICU.
During
your stay in the CICU you will be cared for and monitored
very closely. A nurse will be at or near your bedside 24
hours a day. Inside your room there will be monitoring equipment
to track your blood pressure, heart rate, breathing, oxygen
levels, urine output and other vital medical information.
During your stay in the CICU your heart transplant surgeon
will be your primary physician.
Your
vital signs will be checked hourly for the first day or
two in the CICU. Most of this information can be collected
without disturbing you while you are resting. Every day
you will have a chest X-ray in your room, a bath and have
your bandages changed.
For
the first few days after surgery, you will spend most of
your time in bed. You can watch television and listen to
music.
For
the first few hours and days in the CICU, you will be monitored
with a lot of different equipment. As you recover from surgery,
much of that equipment be removed and you will be able to
get up out of bed, sit in the chair and walk around your
bedside.
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Monitoring
equipment
There will be several medical devices connected to you to
help us care for you during your stay in the CICU. Most
of the equipment is put into place in the Operating Room
after you are asleep. We encourage that you read through
this description carefully and ask questions about things
you do not understand.
An Endotracheal
tube is placed in your mouth as a breathing tube. After
you are asleep in the Operating Room this plastic tube is
placed in your mouth and passed into your windpipe. The
breathing tube is taped to your cheek and connected to a
mechanical respirator (also called the "ventilator").
The ventilator breathes for you during surgery and in the
CICU until you are strong enough to breathe on your own.
While you are on the ventilator you will not be able to
talk. You will still be able to communicate by nodding or
shaking your head. When the tube is removed, an oxygen mask
will be used to supply you with additional oxygen.
A Nasogastric
tube (NG tube) keeps air and fluid from collecting in your
stomach. This plastic tube is passed through your nose and
into your stomach. The NG tube will be removed as soon as
you are ready to take food and beverages, usually once we
can hear normal bowel sounds and you have passed gas.
A Bandage
is placed on the right side of your neck. This bandage covers
a special intravenous line or catheter that will be used
to monitor you heart and lungs.
Over
the incisions where the surgery was performed, bandages
and tape are placed and changed daily. You will also have
patches, about the size of silver dollars, placed on your
skin near your shoulders and sides. These patches are connected
to the electrocardiogram or EKG monitor above your bed.
The EKG monitors your heart rate and rhythm of your heartbeat.
Pacemaker wires are placed in the Operating Room and come
out your chest wall. Your new heart needs to be paced for
a few days after surgery.
Chest
tubes are below the chest incision. These tubes are flexible,
plastic tubes that pass through your skin and are placed
around the area where the surgery was performed. The chest
tubes keep air and fluid from collecting in your chest and
help your lungs expand. These tubes are connected to airtight
containers located on the side of your bed. These tubes
usually stay in place for only two to three days. After
surgery your body may swell - particularly in your face,
hands, abdomen, feet or legs. Swelling will worsen over
the first one to two days before improving. This is normal
and it may take a few weeks until it disappears.
A small
rubber catheter checks the function of your kidneys after
surgery. It is placed into your bladder after you are asleep
in surgery. Your urine is collected and measured every hour.
The catheter usually stays in place for two to three days
after surgery. The amount of liquid you will be allowed
to drink will be limited until you move out of the CICU.
Two
intravenous catheters or IV's on each arm are placed into
the artery of your wrist. This measures your blood pressure
collects blood samples so nurses don't disturb you while
you're resting. Until you are fully awake, your hands will
be restrained with soft cotton straps. This is for your
own protection so that you don't accidentally move your
arms too much and disconnect an IV catheter or monitoring
tube.
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Length
of CICU stay
Length of stay in the CICU will vary from individual to
individual. The usual CICU stay is between four to seven
days. When you are transferred from the CICU, you will go
to a private room until you are discharged from the hospital.
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Care
after surgery
It is common to have some pain after transplant surgery.
You will be offered IV pain medication. The nurses will
ask you to rate your pain on a scale of one-to-ten (one
for least or no pain and 10 for worst pain). As soon as
you can take food and liquids, the pain medications will
be given by mouth.
After
your stay in the CICU you will be moved to a private room.
It is necessary to stay in a private room in order to decrease
the number of people with whom you come into contact and
limit your exposure to infection or illness. During the
first few weeks after the transplant you will be especially
vulnerable to infections.
During
the remainder of your hospital stay we again ask that visitors
be limited to immediate family and clergy members. Family
members and any other visitors with a cold or any other
kind of illness should be asked not to visit with you directly,
but use the telephone instead.
You
may walk around the hospital floor during low-traffic periods
in the morning and late evenings after visiting hours. You
should always wear a mask when you are outside your room
and especially when you go to have any tests such as an
X-ray.
Unfortunately,
we can not allow fresh flowers or plants of any kind in
your room after the transplant because they contain bacteria.
Please let your family and friends know about the "no
flowers" policy.
During
your hospital stay after surgery, you and your family will
be involved in a number of activities designed to:
-
Help you recover from surgery
-
Monitor the function of your new heart
-
Prepare you for going home
-
Inform you about your health care and lifestyle after
hospital discharged
The
first step in the recovery process will involve a combination
of chest physiotherapy, proper nutrition and exercise with
appropriate periods of rest.
Chest
physiotherapy (CPT) is extremely important after a heart
transplant. CPT involves activities designed to keep your
lungs clear of secretions and prevent lung collapse and
pneumonia.
Deep
breathing exercises expand your lungs to their fullest capacity.
These exercises help to open up even the tiniest airways
in your lungs. They also help to strengthen your breathing
muscles, especially the diaphragm and muscles between your
ribs.
The
incentive spirometer is a small, portable breathing exerciser
that helps you to breathe more effectively. By setting the
indicator on the incentive spirometer you set your goal
of how much air you want to breathe in. Next, you simply
place your lips around the mouthpiece and inhale until the
blue disk moves to the mark of your goal. You should use
the incentive spirometer five to seven times every two hours
while you are awake (about eight times per day).
Deep
breathing exercises, use of the incentive spirometer and
chest percussion all may produce coughing. Though at times
uncomfortable, coughing itself is important because it helps
to clear secretions from your lungs. One activity you can
do to help make coughing easier is to splint your chest
with a pillow or rolled up blanket. Simply hold or "hug"
the pillow against your chest whenever you cough. In addition
to splinting, your doctors will be sure to provide you with
medicines to help ease the aches and discomfort associated
with chest therapy.
After
your hospital discharge, you must make regular visits to
the clinic. An important part of these visits is a check
of the amount of Cyclosporine in your blood stream. A blood
sample will be taken to check this.
On the
day of a regular clinic visit do not take your Cyclosporine
before clinic. Bring your Cyclosporine and other medications
with you.
After
two years, follow up clinic visits are required every six
months.
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Exercise
After surgery, exercise will be an important part of your
rehabilitation program. In the beginning, exercises will
be directed toward maintaining the flexibility of your joints
and tone of your muscles. Initially, physical therapists
and nurses assist you with these exercises until you are
strong enough to perform them on your own. At first, you
will walk with assistance can progress to longer periods
of exercise designed to increase your endurance.
At first,
your ability to exercise will be limited. Once you are out
of bed you will start with short walks (50 to 100 feet)
assisted by others or with a walker. By gradually increasing
the distance you walk each day, most patients can walk a
mile a day by the end of the third or fourth postoperative
week.
For
the first several weeks, as your body gets used to your
new heart, it is common to fatigue easily and to become
short of breath quickly. This can be frustrating. It will
take your body and your mind a little while to get used
to the new heart.
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Immune
system, rejection, infection and medications
In addition to chest physiotherapy and exercise an equally
important part of your follow-up care involves taking special
medications. To understand why these medicines are important
you must first understand how the immune system of your
body.
Your
body's immune system works to prevent, limit the spread
and fight infections. It also rids your body of foreign
living substances. Bacteria live all around us and inside
of us, especially in our mouths and intestines. If these
bacteria are not controlled by the immune system, they could
overwhelm us. Normally, if you cut yourself and bacteria
enter the wound, these bacteria usually do not spread to
other areas of your body. This is because the immune system
causes white blood cells to rush in and hold the bacteria
in place until they are destroyed. The immune system is
very helpful in limiting the spread of infections from one
place in our body to another.
If you
have a bad cold or flu that affects your entire body, your
immune system works to rid your body of the bacteria or
virus. Proper nutrition and medications such as antibiotics,
also help the immune system fight a whole-body infection.
Rejection
is an important issue in transplantation. A special way
that the immune system works is to fight foreign substances
that may enter your body. Foreign living objects can include
bacteria, viruses or living tissue from another human being
(such as a transplanted organ). The technical name for a
foreign living object is an antigen. When the body recognizes
an antigen, it tries to make specific cells to fight the
antigen called antibodies. Different antigens require different
antibodies to fight them. Think about an antigen as a lock
on a door that needs exactly the right key to open it (antibody).
Your immune system has the ability to make a lot of different
antibodies for a lot of different antigens.
Unfortunately,
your body may recognize your new heart as an antigen and
will try to make antibodies to fight against it. Therefore,
after the transplant your immune system must be suppressed
to prevent the formation of antibodies that would cause
your body to reject your new heart.
Medications can suppress of your immune system through immunosuppression.
It is important to remember that when trying to prevent rejection
of your new heart by immunosuppression, you become vulnerable to
infections with bacteria and viruses. Some medications
must be take every day for the rest of your life.
Statistics
Success rate and various other statistics regarding the
Shands Transplant Center at UF are available from the Scientific
Registry of Transplant Recipients at ustransplant.org.
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